Asialoglycoprotein Receptor 1 antibody

Catalog No. ABIN1839609

This anti-Asialoglycoprotein Receptor 1 antibody is a Mouse Monoclonal antibody detecting Asialoglycoprotein Receptor 1 in WB, IHC, IHC (fro) and FACS. Suitable for Human.

Quick Overview for Asialoglycoprotein Receptor 1 antibody (ABIN1839609)

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Asialoglycoprotein Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)

Clone: 8D7

Product Details anti-Asialoglycoprotein Receptor 1 Antibody

Specificity: The asialoglycoprotein receptor (ASGPR) is a transmembrane glycoprotein (42 kD) which mediates binding, internalization and degradation of extracellular glycoproteins that have exposed terminal galactose residues. The receptor is expressed on the surface of the hepatocytes in a polar manner, i. e. it is present on the sinusoidal and lateral plasma membranes but not on the bile canalicular membrane. The mammalian hepatic ASGPR mediates the endocytosis and degradation of serum proteins from which terminal sialic residues have been removed.

Purification: Purified

Immunogen: Crude rat liver membrane extracts.

Type of Immunogen: Membrane extract

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, IHC, IHC-Fr, WB

Usage: For use in Western blot, non-reducing conditions are required.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide, 0.1 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4°C.

Target Details for Asialoglycoprotein Receptor 1

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Alternative Name: ASGR1 / ASGPR

Background: Name/Gene ID: ASGR1

Synonyms: ASGR1, ASGPR1, ASGPR, ASGPR 1, Asialoglycoprotein receptor 1, Hepatic lectin H1, HL-1, ASGP-R 1, CLEC4H1

Gene ID: 432

UniProt: P07306

Pathways: Thyroid Hormone Synthesis