SORL1 antibody (C-Term)

Catalog No. ABIN184579

This Goat Polyclonal antibody specifically detects SORL1 in ELISA and IF. It exhibits reactivity toward Human.It has been mentioned in 1 publication

Quick Overview for SORL1 antibody (C-Term) (ABIN184579)

Target: SORL1 (Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This SORL1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Grade: Verified

Product Details anti-SORL1 Antibody

Binding Specificity: C-Term

Purpose: SORL1 / LR11 (C Terminus)

Sequence: TGFSDDVPMV IA

Cross-Reactivity: Cow, Dog, Human, Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-TGFSDDVPMVIA, from the C Terminus of the protein sequence according to NP_003096.1.

Isotype: IgG

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:32000.

Comment:

Immunofluorescence: Strong expression of the protein seen in A431 and HepG2 cells. Recommended concentration: 10μg/ml.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

References for anti-SORL1 antibody (ABIN184579)

Kim, Lee, Lee, Kim, Song, Huh, Lee, Kim, Kim, Hong, Shim, Chang: "Implication of mouse Vps26b-Vps29-Vps35 retromer complex in sortilin trafficking." in: Biochemical and biophysical research communications, Vol. 403, Issue 2, pp. 167-71, (2010) (PubMed).

Target Details for SORL1

Target: SORL1 (Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))

Alternative Name: SORL1

Background: SORL1, LR11, sortilin-related receptor, L(DLR class) A repeats-containing, LRP9, SORLA, gp250, SorLA-1, mosaic protein LR11, C11orf32, FLJ21930, FLJ39258, sortilin-related receptor containing LDLR class A repeats

Gene ID: 6653

NCBI Accession: NP_003096

Pathways: Smooth Muscle Cell Migration