TDGF1 antibody

Catalog No. ABIN1846225

Product Details anti-TDGF1 Antibody

Target: TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TDGF1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Ascitic fluid containing 0.03% sodium azide.

Immunogen: Purified recombinant fragment of human TDGF1 expressed in E. Coli.

Isotype: IgG1

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C.

Target Details for TDGF1

Target: TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Alternative Name: TDGF1 (TDGF1 Products)

Synonyms: CR antibody, CRGF antibody, CRIPTO antibody, CR1 antibody, cripto antibody, cb85 antibody, tdgf1 antibody, wu:fe01d04 antibody, zgc:109829 antibody, Cripto-1 antibody, cr1 antibody, cr1a antibody, frl-1 antibody, frl1 antibody, xcr1 antibody, TDGF1 antibody, tdgf3 antibody, cripto-3 antibody, teratocarcinoma-derived growth factor 1 antibody, teratocarcinoma-derived growth factor 1, member 3 L homeolog antibody, teratocarcinoma-derived growth factor 1, member 1 antibody, TDGF1 antibody, Tdgf1 antibody, tdgf1 antibody, tdgf1.3.L antibody, tdgf1.1 antibody

Background: This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects.The cripto gene is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers. It could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.Tissue specificity: Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts.

Molecular Weight: 21 kDa

Pathways: EGFR Signaling Pathway