Teratocarcinoma-Derived Growth Factor 1 (TDGF1) antibody

Details for Product No. ABIN1846225
Target
Reactivity
Human
94
33
23
Host
Mouse
68
22
7
2
Clonality
Monoclonal
Conjugate
Un-conjugated
11
10
10
5
4
4
3
2
2
2
2
2
2
2
2
2
2
Application
ELISA, Western Blotting (WB)
50
41
35
26
9
4
4
4
2
2
1
Options
Immunogen Purified recombinant fragment of human TDGF1 expressed in E. Coli.
Isotype IgG1
Purification Ascitic fluid containing 0.03% sodium azide.
Target
Alternative Name TDGF1 (TDGF1 Antibody Abstract)
Background This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects.The cripto gene is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers. It could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.Tissue specificity: Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts.
Molecular Weight 21 kDa
Pathways EGFR Signaling Pathway
Restrictions For Research Use only
Format Liquid
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Images
Image no. 1 for anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) antibody (ABIN1846225) anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) antibody (Image 1)
Image no. 2 for anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) antibody (ABIN1846225) anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) antibody (Image 2)