GLUT4 antibody (AA 224-353)

Catalog No. ABIN1846354

Product Details anti-GLUT4 Antibody

Target: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Binding Specificity: AA 224-353

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This GLUT4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (fixed cells) (IF/ICC), Flow Cytometry (FACS)

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human SLC2A4 (AA: 224-353) expressed in E. coli.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Target Details for GLUT4

Target: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Alternative Name: SLC2A4 (SLC2A4 Products)

Background: This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter.In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue.Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane.Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).

Molecular Weight: 54.8 kDa

Gene ID: 6517

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Proton Transport, Brown Fat Cell Differentiation, Warburg Effect