CCKAR antibody (Internal Region)

Catalog No. ABIN185408

The Goat Polyclonal anti-CCKAR antibody has been validated for ELISA and IHC. It is suitable to detect CCKAR in samples from Human. There is 1 publication available.

Quick Overview for CCKAR antibody (Internal Region) (ABIN185408)

Target: CCKAR (Cholecystokinin A Receptor (CCKAR))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CCKAR antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Grade: Verified

Product Details anti-CCKAR Antibody

Binding Specificity: Internal Region

Purpose: CCKAR

Sequence: FEASQKKSAK ERKPST

Cross-Reactivity: Human

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-FEASQKKSAKERKPST, from the internal region of the protein sequence according to NP_000721.1.

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry: In paraffin embedded Human Pancreas shows strong staning in Islets of Langerhans. Recommended concentration, 2-4 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:128000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

References for anti-CCKAR antibody (ABIN185408)

El-Kouhen, Morisset: "Control of somatostatin (SS) secretion by CCK-1 and CCK-2 receptors' occupation in RIN-14B cells, a rat pancreatic islet cell line." in: Pancreas, Vol. 39, Issue 2, pp. 127-34, (2010) (PubMed).

Target Details for CCKAR

Target: CCKAR (Cholecystokinin A Receptor (CCKAR))

Alternative Name: CCKAR

Background: CCKAR, cholecystokinin A receptor , HGNC:1570, CCK-A, CCK1-R, CCKRA, cholecystokinin type-A receptor, cholecystokinin-1 receptor

Gene ID: 886, 12425, 24889

NCBI Accession: NP_000721

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Feeding Behaviour