MVP antibody

Catalog No. ABIN187327

This Mouse Monoclonal antibody specifically detects MVP in WB, IF and IHC (p). It exhibits reactivity toward Human.

Quick Overview for MVP antibody (ABIN187327)

Target: MVP (Major Vault Protein (MVP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MVP antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MVP-37

Product Details anti-MVP Antibody

Specificity: This antibody reacts with an internal epitope of MVP/LRP (p110) accordingly to an increase in the number of vault particles. The MVP/LRP (p110) is strongly overexpressed in various human non-P-glycoprotein MDR tumor cell lines.

Isotype: IgG2b

Application Details

Application Notes: Western blotting: Use 1:50 dilution (chemi-luminescence). Immunohistochemistry: Use 1:20-50 dilution on 4% paraformaldehyde fixed cytospin preparations or frozen tissue sections. The following pretreatment is recommended: 10 min 20mM glycine (pH 7.5) and 10 min 6N guanidine hydrochloride in 50 mM Tris-HCl (pH 7.5). MVP-37 performs well on paraffin-embedded tissue sections. The optimal dilution for a specific application should be determined by the researcher. Product Specific

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody contains approximately 250ug of immunoglobulin per ml. The solution contains 1% BSA and 0.1% sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for MVP

Target: MVP (Major Vault Protein (MVP))

Alternative Name: Major Vault Protein