ACAA1 antibody (AA 147-176)

Catalog No. ABIN1881041

The Rabbit Polyclonal anti-ACAA1 antibody has been validated for WB. It is suitable to detect ACAA1 in samples from Human. There are 5+ publications available.

Quick Overview for ACAA1 antibody (AA 147-176) (ABIN1881041)

Target: ACAA1 (Acetyl-CoA Acyltransferase 1 (ACAA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACAA1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB41788

Product Details anti-ACAA1 Antibody

Binding Specificity: AA 147-176

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ACAA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-176 amino acids from the Central region of human ACAA1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-ACAA1 antibody (ABIN1881041)

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Han, Lan, Park, Lee, Park, Ahn, Shin, Kang, Koo, Seo, Choi, Ahn, Chanock, Kim, Rothman, Kang: "Polymorphisms in innate immunity genes and risk of childhood leukemia." in: Human immunology, Vol. 71, Issue 7, pp. 727-30, (2010) (PubMed).

Rajaraman, Brenner, Neta, Pfeiffer, Wang, Yeager, Thomas, Fine, Linet, Rothman, Chanock, Inskip: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, (2010) (PubMed).

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

Rajaraman, Brenner, Butler, Wang, Pfeiffer, Ruder, Linet, Yeager, Wang, Orr, Fine, Kwon, Thomas, Rothman, Inskip, Chanock: "Common variation in genes related to innate immunity and risk of adult glioma." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 5, pp. 1651-8, (2009) (PubMed).

Target Details for ACAA1

Target: ACAA1 (Acetyl-CoA Acyltransferase 1 (ACAA1))

Alternative Name: ACAA1

Background: This gene encodes an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants.

Molecular Weight: 44292

NCBI Accession: NP_001123882, NP_001598

UniProt: P09110

Pathways: Monocarboxylic Acid Catabolic Process