Liver Arginase antibody (C-Term)

Catalog No. ABIN1881067

This Rabbit Polyclonal antibody specifically detects Liver Arginase in WB. It exhibits reactivity toward Rat and has been mentioned in 3+ publications.

Quick Overview for Liver Arginase antibody (C-Term) (ABIN1881067)

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Liver Arginase antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB38664

Product Details anti-Liver Arginase Antibody

Binding Specificity: AA 292-318, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Rat Arg1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-318 amino acids from the C-terminal region of rat Arg1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-Liver Arginase antibody (ABIN1881067)

Warnken, Haag, Matthiesen, Juergens, Racké: "Species differences in expression pattern of arginase isoenzymes and differential effects of arginase inhibition on collagen synthesis in human and rat pulmonary fibroblasts." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 381, Issue 4, pp. 297-304, (2010) (PubMed).

Kim, Bugaj, Oh, Bivalacqua, Ryoo, Soucy, Santhanam, Webb, Camara, Sikka, Nyhan, Shoukas, Ilies, Christianson, Champion, Berkowitz: "Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 107, Issue 4, pp. 1249-57, (2009) (PubMed).

Deng, He, Qiu, Lorber, Bryson, Filbin: "Increased synthesis of spermidine as a result of upregulation of arginase I promotes axonal regeneration in culture and in vivo." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 30, pp. 9545-52, (2009) (PubMed).

Target Details for Liver Arginase

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Alternative Name: Arg1

Background: Catalyzes the hydrolysis of arginine to ornithine and urea in arginine metabolism, regulates nitric oxide production [RGD].

Molecular Weight: 34973

NCBI Accession: NP_058830

UniProt: P07824

Pathways: Cellular Response to Molecule of Bacterial Origin