BLMH antibody (AA 212-242)

Catalog No. ABIN1881113

The Rabbit Polyclonal anti-BLMH antibody has been validated for WB and IHC (p). It is suitable to detect BLMH in samples from Human, Rat and Mouse. There are 2+ publications available.

Quick Overview for BLMH antibody (AA 212-242) (ABIN1881113)

Target: BLMH (Bleomycin Hydrolase (BLMH))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BLMH antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-BLMH Antibody

Binding Specificity: AA 212-242

Predicted Reactivity: Rb

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BLMH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-242 amino acids from the Central region of human BLMH.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-BLMH antibody (ABIN1881113)

Ferrando, Velasco, Campo, Lopez-Otin: "Cloning and expression analysis of human bleomycin hydrolase, a cysteine proteinase involved in chemotherapy resistance." in: Cancer research, Vol. 56, Issue 8, pp. 1746-50, (1996) (PubMed).

Brömme, Rossi, Smeekens, Anderson, Payan: "Human bleomycin hydrolase: molecular cloning, sequencing, functional expression, and enzymatic characterization." in: Biochemistry, Vol. 35, Issue 21, pp. 6706-14, (1996) (PubMed).

Target Details for BLMH

Target: BLMH (Bleomycin Hydrolase (BLMH))

Alternative Name: BLMH

Background: The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity (By similarity).

Molecular Weight: 52562

NCBI Accession: NP_000377

UniProt: Q13867