Cited in 3+ publications.
The Rabbit Polyclonal anti-DAP antibody (Clone RB44458) (ABIN1881249) specifically detects DAP in WB.
The antibody is reactive with Human samples.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This DAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-38 amino acids from the N-terminal region of human DAP.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Koren, Reem, Kimchi: "DAP1, a novel substrate of mTOR, negatively regulates autophagy." in: Current biology : CB, Vol. 20, Issue 12, pp. 1093-8, (2010) (PubMed).
Gauci, Helbig, Slijper, Krijgsveld, Heck, Mohammed: "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach." in: Analytical chemistry, Vol. 81, Issue 11, pp. 4493-501, (2009) (PubMed).
Zougman, Wiśniewski: "Beyond linker histones and high mobility group proteins: global profiling of perchloric acid soluble proteins." in: Journal of proteome research, Vol. 5, Issue 4, pp. 925-34, (2006) (PubMed).
Target
DAP
(Death-Associated Protein (DAP))
Alternative Name
DAP
Background
Negative regulator of autophagy. Involved in mediating interferon-gamma-induced cell death.