DNAI2 antibody (C-Term)

Catalog No. ABIN1881264

Cited in 3+ publications. The Rabbit Polyclonal anti-DNAI2 antibody (Clone RB41653) (ABIN1881264) specifically detects DNAI2 in WB. The antibody is reactive with Human samples.

Quick Overview for DNAI2 antibody (C-Term) (ABIN1881264)

Target: DNAI2 (Dynein, Axonemal, Intermediate Chain 2 (DNAI2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAI2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB41653

Product Details anti-DNAI2 Antibody

Binding Specificity: AA 484-513, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DNAI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 484-513 amino acids from the C-terminal region of human DNAI2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-DNAI2 antibody (ABIN1881264)

Loges, Olbrich, Fenske, Mussaffi, Horvath, Fliegauf, Kuhl, Baktai, Peterffy, Chodhari, Chung, Rutman, OCallaghan, Blau, Tiszlavicz, Voelkel, Witt, Zietkiewicz, Neesen, Reinhardt, Mitchison, Omran: "DNAI2 mutations cause primary ciliary dyskinesia with defects in the outer dynein arm." in: American journal of human genetics, Vol. 83, Issue 5, pp. 547-58, (2008) (PubMed).

Pennarun, Chapelin, Escudier, Bridoux, Dastot, Cacheux, Goossens, Amselem, Duriez: "The human dynein intermediate chain 2 gene (DNAI2): cloning, mapping, expression pattern, and evaluation as a candidate for primary ciliary dyskinesia." in: Human genetics, Vol. 107, Issue 6, pp. 642-9, (2001) (PubMed).

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).

Target Details for DNAI2

Target: DNAI2 (Dynein, Axonemal, Intermediate Chain 2 (DNAI2))

Alternative Name: DNAI2

Background: The protein encoded by this gene belongs to the dynein intermediate chain family, and is part of the dynein complex of respiratory cilia and sperm flagella. Mutations in this gene are associated with primary ciliary dyskinesia type 9. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Molecular Weight: 68821

NCBI Accession: NP_001166281, NP_075462

UniProt: Q9GZS0