The Rabbit Polyclonal anti-FKBPL antibody has been validated for WB, FACS and IHC (p). It is suitable to detect FKBPL in samples from Human. There is 1 publication available.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This FKBPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 264-292 amino acids from the C-terminal region of human FKBPL.
FKBPL
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
McKeen, Byrne, Jithesh, Donley, Valentine, Yakkundi, ORourke, Swanton, McCarthy, Hirst, Robson: "FKBPL regulates estrogen receptor signaling and determines response to endocrine therapy." in: Cancer research, Vol. 70, Issue 3, pp. 1090-100, (2010) (PubMed).
Target
FKBPL
(FK506 Binding Protein Like (FKBPL))
Alternative Name
FKBPL
Background
FKBPL has similarity to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The encoded protein is thought to have a potential role in the induced radioresistance. Also it appears to have some involvement in the control of the cell cycle.