GDI1 antibody (C-Term)

Catalog No. ABIN1881368

The Rabbit Polyclonal anti-GDI1 antibody has been validated for WB. It is suitable to detect GDI1 in samples from Human, Mouse and Rat. There are 4+ publications available.

Quick Overview for GDI1 antibody (C-Term) (ABIN1881368)

Target: GDI1 (GDP Dissociation Inhibitor 1 (GDI1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDI1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB42409

Product Details anti-GDI1 Antibody

Binding Specificity: AA 415-443, C-Term

Predicted Reactivity: B, Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GDI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 415-443 amino acids from the C-terminal region of human GDI1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. WB: 1:1000-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-GDI1 antibody (ABIN1881368)

Massignan, Biasini, Lauranzano, Veglianese, Pignataro, Fioriti, Harris, Salmona, Chiesa, Bonetto: "Mutant prion protein expression is associated with an alteration of the Rab GDP dissociation inhibitor alpha (GDI)/Rab11 pathway." in: Molecular & cellular proteomics : MCP, Vol. 9, Issue 4, pp. 611-22, (2010) (PubMed).

Martins-de-Souza, Schmitt, Röder, Lebar, Schneider-Axmann, Falkai, Turck: "Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia." in: Journal of psychiatric research, Vol. 44, Issue 14, pp. 989-91, (2010) (PubMed).

Chen, Deng, Zhang, Yang, Xie, Xu: "GDI-1 preferably interacts with Rab10 in insulin-stimulated GLUT4 translocation." in: The Biochemical journal, Vol. 422, Issue 2, pp. 229-35, (2009) (PubMed).

Zhang, DU, Zheng, Gao, Huang, Li, Chen, Zhang: "[Relationship between the polymorphisms of GDI1, children NSMR and their intelligence in Qinba region]." in: Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji, Vol. 30, Issue 5, pp. 590-4, (2008) (PubMed).

Target Details for GDI1

Target: GDI1 (GDP Dissociation Inhibitor 1 (GDI1))

Alternative Name: GDI1

Background: GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.

Molecular Weight: 50583

NCBI Accession: NP_001484

UniProt: P31150