GGT1 antibody (N-Term)

Catalog No. ABIN1881373

This Rabbit Polyclonal antibody specifically detects GGT1 in WB. It exhibits reactivity toward Human and Mouse and has been mentioned in 4+ publications.

Quick Overview for GGT1 antibody (N-Term) (ABIN1881373)

Target: GGT1 (gamma Glutamyltransferase 1 (GGT1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GGT1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB41020

Product Details anti-GGT1 Antibody

Binding Specificity: AA 124-152, N-Term

Predicted Reactivity: Pig, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GGT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-152 amino acids from the N-terminal region of human GGT1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-GGT1 antibody (ABIN1881373)

Ikeda, Maki, Yin, Kawate, Adachi, Ohnaka, Takayanagi, Kono: "Relation of coffee consumption and serum liver enzymes in Japanese men and women with reference to effect modification of alcohol use and body mass index." in: Scandinavian journal of clinical and laboratory investigation, Vol. 70, Issue 3, pp. 171-9, (2010) (PubMed).

Fujita, Ueno, Hata: "Association of gamma-glutamyltransferase with incidence of type 2 diabetes in Japan." in: Experimental biology and medicine (Maywood, N.J.), Vol. 235, Issue 3, pp. 335-41, (2010) (PubMed).

Speliotes, Butler, Palmer, Voight, Hirschhorn: "PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease." in: Hepatology (Baltimore, Md.), Vol. 52, Issue 3, pp. 904-12, (2010) (PubMed).

Kamatani, Matsuda, Okada, Kubo, Hosono, Daigo, Nakamura, Kamatani: "Genome-wide association study of hematological and biochemical traits in a Japanese population." in: Nature genetics, Vol. 42, Issue 3, pp. 210-5, (2010) (PubMed).

Target Details for GGT1

Target: GGT1 (gamma Glutamyltransferase 1 (GGT1))

Alternative Name: GGT1

Background: The enzyme encoded by this gene catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein, and is present in tissues involved in absorption and secretion. This enzyme is a member of the gamma-glutamyltransferase protein family, of which many members have not yet been fully characterized and some of which may represent pseudogenes. This gene is classified as type I gamma-glutamyltransferase. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Molecular Weight: 61410

NCBI Accession: NP_001027536, NP_001027537, NP_005256, NP_038347

UniProt: P19440