GGT1 antibody (N-Term)

Catalog No. ABIN6261947

Product Details anti-GGT1 Antibody

Target: GGT1 (gamma Glutamyltransferase 1 (GGT1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GGT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: GGT1 Antibody detects endogenous levels of total GGT1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GGT1, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for GGT1

Target: GGT1 (gamma Glutamyltransferase 1 (GGT1))

Alternative Name: GGT1 (GGT1 Products)

Synonyms: ggt1 antibody, zgc:64172 antibody, CD224 antibody, D22S672 antibody, D22S732 antibody, GGT antibody, GGT 1 antibody, GTG antibody, GGT-1 antibody, Ggtp antibody, dwg antibody, GGLUT antibody, Ggt antibody, GGT2 antibody, cd224 antibody, ggt antibody, gtg antibody, GGT1 antibody, ggt1-a antibody, gamma-glutamyltransferase 1a antibody, gamma-glutamyltransferase 1 antibody, gamma-glutamyltranspeptidase 1 antibody, gamma-glutamyltransferase 1 L homeolog antibody, gamma-glutamyltransferase antibody, gamma-glutamyltranspeptidase Ggt1 antibody, ggt1a antibody, GGT1 antibody, Ggt1 antibody, ggt1 antibody, LOC470168 antibody, ggt1.L antibody, ggt antibody, Bcep18194_A6223 antibody, h16_A1098 antibody, Shewana3_2487 antibody, Bcep1808_2978 antibody

Background:

Description: Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Isoform 3 seems to be inactive.

Gene: GGT1

Molecular Weight: 60kDa

Gene ID: 2678

UniProt: P19440