PRRX2 antibody (C-Term)

Catalog No. ABIN1881691

This Rabbit Polyclonal antibody specifically detects PRRX2 in WB. It exhibits reactivity toward Mouseand has been mentioned in 1 publication.

Quick Overview for PRRX2 antibody (C-Term) (ABIN1881691)

Target: PRRX2 (Paired Related Homeobox 2 (PRRX2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRRX2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB37428

Product Details anti-PRRX2 Antibody

Binding Specificity: AA 223-250, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PRRX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-250 amino acids from the C-terminal region of human PRRX2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-PRRX2 antibody (ABIN1881691)

Gervais, Mauvieux, Perrusson, Hélias, Struski, Leymarie, Lioure, Lessard: "A new translocation t(9;11)(q34;p15) fuses NUP98 to a novel homeobox partner gene, PRRX2, in a therapy-related acute myeloid leukemia." in: Leukemia, Vol. 19, Issue 1, pp. 145-8, (2004) (PubMed).

Target Details for PRRX2

Target: PRRX2 (Paired Related Homeobox 2 (PRRX2))

Alternative Name: PRRX2

Background: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.

Molecular Weight: 27079

NCBI Accession: NP_057391

UniProt: Q99811