PSMD6 antibody (AA 154-182)

Catalog No. ABIN1881700

This Rabbit Polyclonal antibody specifically detects PSMD6 in WB. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for PSMD6 antibody (AA 154-182) (ABIN1881700)

Target: PSMD6 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 6 (PSMD6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD6 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB42752

Product Details anti-PSMD6 Antibody

Binding Specificity: AA 154-182

Predicted Reactivity: B, D, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PSMD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-182 amino acids from the Central region of human PSMD6.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-PSMD6 antibody (ABIN1881700)

Tanaka, Scheet, Giusti, Bandinelli, Piras, Usala, Lai, Mulas, Corsi, Vestrini, Sofi, Gori, Abbate, Guralnik, Singleton, Abecasis, Schlessinger, Uda, Ferrucci: "Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations." in: American journal of human genetics, Vol. 84, Issue 4, pp. 477-82, (2009) (PubMed).

Bouwmeester, Bauch, Ruffner, Angrand, Bergamini, Croughton, Cruciat, Eberhard, Gagneur, Ghidelli, Hopf, Huhse, Mangano, Michon, Schirle, Schlegl, Schwab, Stein, Bauer, Casari, Drewes, Gavin, Jackson et al.: "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. ..." in: Nature cell biology, Vol. 6, Issue 2, pp. 97-105, (2004) (PubMed).

Margottin-Goguet, Hsu, Loktev, Hsieh, Reimann, Jackson: "Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase." in: Developmental cell, Vol. 4, Issue 6, pp. 813-26, (2003) (PubMed).

Target Details for PSMD6

Target: PSMD6 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 6 (PSMD6))

Alternative Name: PSMD6

Background: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.

Molecular Weight: 45531

NCBI Accession: NP_001258708, NP_001258709, NP_001258710, NP_055629

UniProt: Q15008

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway