This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This RXFP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 685-713 amino acids from the C-terminal region of human RXFP1.
LGR7 antibody, RXFPR1 antibody, Gm1018 antibody, Lgr7 antibody, RXFP2 antibody, relaxin/insulin like family peptide receptor 1 antibody, relaxin/insulin-like family peptide receptor 1 antibody, RXFP1 antibody, rxfp1 antibody, Rxfp1 antibody
Background
Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.