ST6GAL1 antibody (AA 178-206)

Catalog No. ABIN1881841

This Rabbit Polyclonal antibody specifically detects ST6GAL1 in WB. It exhibits reactivity toward Human and has been mentioned in 4+ publications.

Quick Overview for ST6GAL1 antibody (AA 178-206) (ABIN1881841)

Target: ST6GAL1 (ST6 beta-Galactosamide alpha-2,6-Sialyltranferase 1 (ST6GAL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ST6GAL1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB41682

Product Details anti-ST6GAL1 Antibody

Binding Specificity: AA 178-206

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ST6GAL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-206 amino acids from the Central region of human ST6GAL1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-ST6GAL1 antibody (ABIN1881841)

Mondal, Chandra, Mandal: "Elevated mRNA level of hST6Gal I and hST3Gal V positively correlates with the high risk of pediatric acute leukemia." in: Leukemia research, Vol. 34, Issue 4, pp. 463-70, (2010) (PubMed).

Lee, Park, Lee: "Adhesion of ST6Gal I-mediated human colon cancer cells to fibronectin contributes to cell survival by integrin beta1-mediated paxillin and AKT activation." in: Oncology reports, Vol. 23, Issue 3, pp. 757-61, (2010) (PubMed).

Daly, Donaldson, Bhatnagar, Shen, Peer, Floratos, Daly, Goldstein, John, Nelson, Graham, Park, Dillon, Bernal, Cordell, Pirmohamed, Aithal, Day: "HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin." in: Nature genetics, Vol. 41, Issue 7, pp. 816-9, (2009) (PubMed).

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).

Target Details for ST6GAL1

Target: ST6GAL1 (ST6 beta-Galactosamide alpha-2,6-Sialyltranferase 1 (ST6GAL1))

Alternative Name: ST6GAL1

Background: This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described.

Molecular Weight: 46605

NCBI Accession: NP_003023, NP_775323, NP_775324

UniProt: P15907