Syntaxin 11 antibody (N-Term)

Catalog No. ABIN1881853

This Rabbit Polyclonal antibody specifically detects Syntaxin 11 in WB. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for Syntaxin 11 antibody (N-Term) (ABIN1881853)

Target: Syntaxin 11 (STX11)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Syntaxin 11 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB40556

Product Details anti-Syntaxin 11 Antibody

Binding Specificity: AA 29-56, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This STX11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-56 amino acids from the N-terminal region of human STX11.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-Syntaxin 11 antibody (ABIN1881853)

Marsh, Satake, Biroschak, Jacobs, Johnson, Jordan, Bleesing, Filipovich, Zhang: "STX11 mutations and clinical phenotypes of familial hemophagocytic lymphohistiocytosis in North America." in: Pediatric blood & cancer, Vol. 55, Issue 1, pp. 134-40, (2010) (PubMed).

zur Stadt, Rohr, Seifert, Koch, Grieve, Pagel, Strauss, Kasper, Nürnberg, Becker, Maul-Pavicic, Beutel, Janka, Griffiths, Ehl, Hennies: "Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11." in: American journal of human genetics, Vol. 85, Issue 4, pp. 482-92, (2009) (PubMed).

Marcelin, Diatloff-Zito, Nicole, Robert: "Developmental methylation program and concerted expression of Stx11 in mouse tissues." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 20, Issue 3, pp. 131-9, (2009) (PubMed).

Target Details for Syntaxin 11

Target: Syntaxin 11 (STX11)

Alternative Name: STX11

Background: This gene encodes a member of the syntaxin family. Syntaxins have been implicated in the targeting and fusion of intracellular transport vesicles. This family member may regulate protein transport among late endosomes and the trans-Golgi network. Mutations in this gene have been associated with familial hemophagocytic lymphohistiocytosis.

Molecular Weight: 33196

NCBI Accession: NP_003755

UniProt: O75558