Syntaxin 7 antibody (N-Term)

Catalog No. ABIN1881855

This anti-Syntaxin 7 antibody is a Rabbit Polyclonal antibody detecting Syntaxin 7 in WB, FACS and IHC (p). Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for Syntaxin 7 antibody (N-Term) (ABIN1881855)

Target: Syntaxin 7 (STX7)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Syntaxin 7 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB21640

Product Details anti-Syntaxin 7 Antibody

Binding Specificity: AA 47-73, N-Term

Predicted Reactivity: B, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This STX7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-73 amino acids from the N-terminal region of human STX7.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-Syntaxin 7 antibody (ABIN1881855)

Steegmaier, Yang, Yoo, Huang, Shen, Yu, Luo, Scheller: "Three novel proteins of the syntaxin/SNAP-25 family." in: The Journal of biological chemistry, Vol. 273, Issue 51, pp. 34171-9, (1999) (PubMed).

Target Details for Syntaxin 7

Target: Syntaxin 7 (STX7)

Alternative Name: STX7

Background: Syntaxin 7 is involved in the ordered fusion of endosomes and lysosomes with the phagosome, where phagocytic cells kill and degrade internalized foreign particles. Syntaxin 7 is found in late endosomes and lysosomes, whereas Syntaxin 12 is localized to the recycling endosome compartment, both are recruited to the phagosome. However, STX12 is acquired earlier before rapidly recycling off the phagosome, whereas STX7 is recruited later and continues to accumulate throughout the phagosome maturation process.

Molecular Weight: 29816

NCBI Accession: NP_003560

UniProt: O15400

Pathways: Synaptic Vesicle Exocytosis