Synaptophysin antibody (C-Term)

Catalog No. ABIN1881862

This Rabbit Polyclonal antibody specifically detects Synaptophysin in WB, IF, IHC (p) and FACS. It exhibits reactivity toward Human and Mouse and has been mentioned in 5+ publications.

Quick Overview for Synaptophysin antibody (C-Term) (ABIN1881862)

Target: Synaptophysin (SYP)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Synaptophysin antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB32966

Product Details anti-Synaptophysin Antibody

Binding Specificity: AA 225-253, C-Term

Predicted Reactivity: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SYP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-253 amino acids from the C-terminal region of human SYP.

Isotype: IgG

Application Details

Application Notes: IF: 1:100. IF: 1:100. WB: 1:2000. IHC-P: 1:1000. IHC-P: 1:1000. FC: 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-Synaptophysin antibody (ABIN1881862)

Ishida, Kushima, Okabe: "Aberrant expression of class III beta-tubulin in basal cell carcinoma of the skin." in: Oncology reports, Vol. 22, Issue 4, pp. 733-7, (2009) (PubMed).

Sterlacci, Fiegl, Hilbe, Auberger, Mikuz, Tzankov: "Clinical relevance of neuroendocrine differentiation in non-small cell lung cancer assessed by immunohistochemistry: a retrospective study on 405 surgically resected cases." in: Virchows Archiv : an international journal of pathology, Vol. 455, Issue 2, pp. 125-32, (2009) (PubMed).

Head, Corrada, Kahle-Wrobleski, Kim, Sarsoza, Goodus, Kawas: "Synaptic proteins, neuropathology and cognitive status in the oldest-old." in: Neurobiology of aging, Vol. 30, Issue 7, pp. 1125-34, (2009) (PubMed).

Gulubova, Vlaykova: "Chromogranin A-, serotonin-, synaptophysin- and vascular endothelial growth factor-positive endocrine cells and the prognosis of colorectal cancer: an immunohistochemical and ultrastructural study." in: Journal of gastroenterology and hepatology, Vol. 23, Issue 10, pp. 1574-85, (2009) (PubMed).

Glantz, Gilmore, Hamer, Lieberman, Jarskog: "Synaptophysin and postsynaptic density protein 95 in the human prefrontal cortex from mid-gestation into early adulthood." in: Neuroscience, Vol. 149, Issue 3, pp. 582-91, (2007) (PubMed).

Target Details for Synaptophysin

Target: Synaptophysin (SYP)

Alternative Name: SYP

Background: Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.[supplied by OMIM].

Molecular Weight: 33845

NCBI Accession: NP_003170

UniProt: P08247

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity