THOC7 antibody (C-Term)

Catalog No. ABIN1881883

This Rabbit Polyclonal antibody specifically detects THOC7 in WB and FACS. It exhibits reactivity toward Human and Mouse and has been mentioned in 4+ publications.

Quick Overview for THOC7 antibody (C-Term) (ABIN1881883)

Target: THOC7 (THO Complex 7 (THOC7))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THOC7 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB24932

Product Details anti-THOC7 Antibody

Binding Specificity: AA 138-166, C-Term

Predicted Reactivity: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This THOC7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-166 amino acids from the C-terminal region of human THOC7.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-THOC7 antibody (ABIN1881883)

Lee, Song, Smith, Kay: "Human corneal endothelial cells employ phosphorylation of p27(Kip1) at both Ser10 and Thr187 sites for FGF-2-mediated cell proliferation via PI 3-kinase." in: Investigative ophthalmology & visual science, Vol. 52, Issue 11, pp. 8216-23, (2011) (PubMed).

Ramachandran, Tran, Klebba-Faerber, Kardinal, Whetton, Tamura: "An ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5." in: RNA (New York, N.Y.), Vol. 17, Issue 11, pp. 1957-66, (2011) (PubMed).

El Bounkari, Guria, Klebba-Faerber, Claussen, Pieler, Griffiths, Whetton, Koch, Tamura: "Nuclear localization of the pre-mRNA associating protein THOC7 depends upon its direct interaction with Fms tyrosine kinase interacting protein (FMIP)." in: FEBS letters, Vol. 583, Issue 1, pp. 13-8, (2008) (PubMed).

Masuda, Das, Cheng, Hurt, Dorman, Reed: "Recruitment of the human TREX complex to mRNA during splicing." in: Genes & development, Vol. 19, Issue 13, pp. 1512-7, (2005) (PubMed).

Target Details for THOC7

Target: THOC7 (THO Complex 7 (THOC7))

Alternative Name: THOC7

Molecular Weight: 23743

NCBI Accession: NP_079351

UniProt: Q6I9Y2