UBR7 antibody (N-Term)

Catalog No. ABIN1881973

This Rabbit Polyclonal antibody specifically detects UBR7 in WB. It exhibits reactivity toward Human. It has been mentioned in 2+ publications

Quick Overview for UBR7 antibody (N-Term) (ABIN1881973)

Target: UBR7 (Ubiquitin Protein Ligase E3 Component N-Recognin 7 (UBR7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBR7 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB40614

Product Details anti-UBR7 Antibody

Binding Specificity: AA 100-128, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This UBR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-128 amino acids from the N-terminal region of human UBR7.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-UBR7 antibody (ABIN1881973)

Lee, Pal, Tasaki, Roy, Jiang, An, Banerjee, Kwon: "Synthetic heterovalent inhibitors targeting recognition E3 components of the N-end rule pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 1, pp. 100-5, (2008) (PubMed).

Kiechl, Werner, Knoflach, Furtner, Willeit, Schett: "The osteoprotegerin/RANK/RANKL system: a bone key to vascular disease." in: Expert review of cardiovascular therapy, Vol. 4, Issue 6, pp. 801-11, (2006) (PubMed).

Target Details for UBR7

Target: UBR7 (Ubiquitin Protein Ligase E3 Component N-Recognin 7 (UBR7))

Alternative Name: UBR7

Background: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific amino-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity).

Molecular Weight: 47999

NCBI Accession: NP_786924

UniProt: Q8N806