USP25 antibody

Catalog No. ABIN1882057

This Mouse Monoclonal antibody specifically detects USP25 in WB. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for USP25 antibody (ABIN1882057)

Target: USP25 (Ubiquitin Specific Peptidase 25 (USP25))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This USP25 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 1277CT376-106-171

Product Details anti-USP25 Antibody

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This USP25 antibody is generated from a mouse immunized with a recombinant protein from human USP25.

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-USP25 antibody (ABIN1882057)

Groet, Ives, Jones, Danton, Flomen, Sheer, Hrascan, Pavelic, Nizetic: "Narrowing of the region of allelic loss in 21q11-21 in squamous non-small cell lung carcinoma and cloning of a novel ubiquitin-specific protease gene from the deleted segment." in: Genes, chromosomes & cancer, Vol. 27, Issue 2, pp. 153-61, (2000) (PubMed).

Valero, Marfany, González-Angulo, González-González, Puelles, Gonzàlez-Duarte: "USP25, a novel gene encoding a deubiquitinating enzyme, is located in the gene-poor region 21q11.2." in: Genomics, Vol. 62, Issue 3, pp. 395-405, (2000) (PubMed).

Target Details for USP25

Target: USP25 (Ubiquitin Specific Peptidase 25 (USP25))

Alternative Name: USP25

Background: Deubiquitinating enzyme that hydrolyzes ubiquitin moieties conjugated to substrates and thus, functions to process newly synthesized Ubiquitin, to recycle ubiquitin molecules or to edit polyubiquitin chains and prevents proteasomal degradation of substrates. Hydrolyzes both 'Lys-48'- and 'Lys-63'-linked tetraubiquitin chains.

Molecular Weight: 122218

UniProt: Q9UHP3