EIF3H antibody (C-Term)

Catalog No. ABIN1882076

Product Details anti-EIF3H Antibody

Target: EIF3H (Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H))

Binding Specificity: AA 234-263, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF3H antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Predicted Reactivity: B, C, X

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This EIF3H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-263 amino acids from the C-terminal region of human EIF3H.

Clone: RB20154

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-EIF3H antibody (ABIN1882076)

Cappuzzo, Varella-Garcia, Rossi, Gajapathy, Valente, Drabkin, Gemmill: "MYC and EIF3H Coamplification significantly improve response and survival of non-small cell lung cancer patients (NSCLC) treated with gefitinib." in: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Vol. 4, Issue 4, pp. 472-8, (2009) (PubMed).

Target Details for EIF3H

Target: EIF3H (Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H))

Alternative Name: EIF3H (EIF3H Products)

Synonyms: EIF3S3 antibody, eIF3-gamma antibody, eIF3-p40 antibody, 1110008A16Rik antibody, 40kD antibody, 9430017H16Rik antibody, EIF3-P40 antibody, EIF3-gamma antibody, Eif3s3 antibody, eif3s3 antibody, eIF-3p40 antibody, En10 antibody, AO090038000435 antibody, EIF3H antibody, eIF3h antibody, BcDNA:GM14618 antibody, CG9124 antibody, Dmel\\CG9124 antibody, eIF-3 antibody, eIF3-S3 antibody, eIf3-p44 antibody, l(2)k09003 antibody, eIF3h-A antibody, eif3h antibody, fj02c04 antibody, wu:fj02c04 antibody, zgc:101085 antibody, eIF3h-B antibody, zgc:123049 antibody, eukaryotic translation initiation factor 3 subunit H antibody, eukaryotic translation initiation factor 3, subunit H antibody, eukaryotic translation initiation factor 3 subunit H S homeolog antibody, eukaryotic translation initiation factor 3 subunit H-like antibody, Eukaryotic initiation factor 3 p40 subunit antibody, eukaryotic translation initiation factor 3, subunit H, a antibody, Eukaryotic translation initiation factor 3 subunit H antibody, translation initiation factor eIF3h (p40) antibody, eukaryotic translation initiation factor 3, subunit H, b antibody, EIF3H antibody, Eif3h antibody, eif3h antibody, eif3h.S antibody, eIF3h antibody, AOR_1_722074 antibody, PAAG_02837 antibody, VDBG_01433 antibody, MGYG_06658 antibody, LOC100196680 antibody, eIF-3p40 antibody, eif3ha antibody, eif-3.H antibody, SPAC821.05 antibody, eif3hb antibody

Background: EIF3H is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Molecular Weight: 39930

NCBI Accession: NP_003747

UniProt: O15372

Pathways: Ribonucleoprotein Complex Subunit Organization