ICAM1 antibody (C-Term)

Catalog No. ABIN1882096

This Rabbit Polyclonal antibody specifically detects ICAM1 in WB and FACS. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for ICAM1 antibody (C-Term) (ABIN1882096)

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICAM1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB20472

Product Details anti-ICAM1 Antibody

Binding Specificity: AA 488-514, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This ICAM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 488-514 amino acids from the C-terminal region of human ICAM1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-ICAM1 antibody (ABIN1882096)

Fang, Yang, Yuan, Gao, Zhou, Chen, Xu: "Myocardin-related transcription factor A mediates OxLDL-induced endothelial injury." in: Circulation research, Vol. 108, Issue 7, pp. 797-807, (2011) (PubMed).

Denkers, de Jong-de Boer, Beelen, Ossenkoppele, Langenhuijsen: "VLA molecule expression may be involved in the release of acute myeloid leukaemic cells from the bone marrow." in: Leukemia research, Vol. 16, Issue 5, pp. 469-74, (1992) (PubMed).

Rössler, Neuchrist, Kitz, Scheiner, Kraft, Lassmann: "Expression of leucocyte adhesion molecules at the human blood-brain barrier (BBB)." in: Journal of neuroscience research, Vol. 31, Issue 2, pp. 365-74, (1992) (PubMed).

Target Details for ICAM1

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Alternative Name: ICAM1

Background: ICAM1 is a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor.

Molecular Weight: 57825

NCBI Accession: NP_000192

UniProt: P05362

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling