Pcp2 antibody (C-Term)

Catalog No. ABIN1882111

This Rabbit Polyclonal antibody specifically detects Pcp2 in IHC (p). It exhibits reactivity toward Mouse and has been mentioned in 3+ publications.

Quick Overview for Pcp2 antibody (C-Term) (ABIN1882111)

Target: Pcp2 (PCP2) (Purkinje Cell Protein 2 (PCP2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Pcp2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB7196

Product Details anti-Pcp2 Antibody

Binding Specificity: AA 91-120, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Mouse Pcp2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-120 amino acids from the C-terminal region of mouse Pcp2.

Isotype: Ig Fraction

Application Details

Application Notes: IHC-P: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-Pcp2 antibody (ABIN1882111)

Guan, Luo, Denker: "Purkinje cell protein-2 (Pcp2) stimulates differentiation in PC12 cells by Gbetagamma-mediated activation of Ras and p38 MAPK." in: The Biochemical journal, Vol. 392, Issue Pt 2, pp. 389-97, (2005) (PubMed).

Saito, Tsumura, Otake, Nishida, Furukawa, Suzuki: "L7/Pcp-2-specific expression of Cre recombinase using knock-in approach." in: Biochemical and biophysical research communications, Vol. 331, Issue 4, pp. 1216-21, (2005) (PubMed).

Zhang, Zhang, Oberdick et al.: "Conservation of the developmentally regulated dendritic localization of a Purkinje cell-specific mRNA that encodes a G-protein modulator: comparison of rodent and human Pcp2(L7) gene structure and..." in: Brain research. Molecular brain research, Vol. 105, Issue 1-2, pp. 1-10, (2002) (PubMed).

Target Details for Pcp2

Target: Pcp2 (PCP2) (Purkinje Cell Protein 2 (PCP2))

Alternative Name: Pcp2

Background: Pcp2 may function as a cell-type specific modulator for G protein-mediated cell signaling. This protein exhibits tissue specificity for cerebellum (Purkinje cells) and retinal bipolar neurons.

Molecular Weight: 13054

NCBI Accession: NP_001123276, NP_032816

UniProt: P12660