ATP1A1 antibody (AA 1-30)

Catalog No. ABIN1882162

This Rabbit Polyclonal antibody specifically detects ATP1A1 in WB. It exhibits reactivity toward Rat and has been mentioned in 3+ publications.

Quick Overview for ATP1A1 antibody (AA 1-30) (ABIN1882162)

Target: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP1A1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB43781

Product Details anti-ATP1A1 Antibody

Binding Specificity: AA 1-30

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Rat Atp1a1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from Rat Atp1a1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-ATP1A1 antibody (ABIN1882162)

Hara, Urayama, Kawakami, Nojima, Nagamune, Kojima, Ohta, Nagano, Nakao: "Primary structures of two types of alpha-subunit of rat brain Na+,K+,-ATPase deduced from cDNA sequences." in: Journal of biochemistry, Vol. 102, Issue 1, pp. 43-58, (1987) (PubMed).

Herrera, Emanuel, Ruiz-Opazo, Levenson, Nadal-Ginard: "Three differentially expressed Na,K-ATPase alpha subunit isoforms: structural and functional implications." in: The Journal of cell biology, Vol. 105, Issue 4, pp. 1855-65, (1987) (PubMed).

Shull, Greeb, Lingrel: "Molecular cloning of three distinct forms of the Na+,K+-ATPase alpha-subunit from rat brain." in: Biochemistry, Vol. 25, Issue 25, pp. 8125-32, (1987) (PubMed).

Target Details for ATP1A1

Target: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Alternative Name: Atp1a1

Background: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.

Molecular Weight: 113054

UniProt: P06685

Pathways: Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Proton Transport, Ribonucleoside Biosynthetic Process