GOLPH3 antibody

Catalog No. ABIN1882249

This Mouse Monoclonal antibody specifically detects GOLPH3 in WB. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for GOLPH3 antibody (ABIN1882249)

Target: GOLPH3 (Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GOLPH3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 905CT9-1-1

Product Details anti-GOLPH3 Antibody

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: Purified His-tagged GOLPH3 protein was used to produced this monoclonal antibody.

Isotype: IgG1

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-GOLPH3 antibody (ABIN1882249)

Zhang, Wang, Liu, Chen, Peng, Liang, Li, Xue, Li, Xia: "Overexpression of GOLPH3 is associated with poor prognosis and clinical progression in pancreatic ductal adenocarcinoma." in: BMC cancer, Vol. 14, pp. 571, (2014) (PubMed).

Nakashima-Kamimura, Asoh, Ishibashi, Mukai, Shidara, Oda, Munakata, Goto, Ohta: "MIDAS/GPP34, a nuclear gene product, regulates total mitochondrial mass in response to mitochondrial dysfunction." in: Journal of cell science, Vol. 118, Issue Pt 22, pp. 5357-67, (2005) (PubMed).

Bell, Ward, Blackstock, Freeman, Choudhary, Lewis, Chotai, Fazel, Gushue, Paiement, Palcy, Chevet, Lafrenière-Roula, Solari, Thomas, Rowley, Bergeron: "Proteomics characterization of abundant Golgi membrane proteins." in: The Journal of biological chemistry, Vol. 276, Issue 7, pp. 5152-65, (2001) (PubMed).

Target Details for GOLPH3

Target: GOLPH3 (Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3))

Alternative Name: GOLPH3

Background: Mediates the cis and medial Golgi localization of mannosyltransferases through direct binding of their cytosolic domains. Involved in modulation of mTOR signaling. Involved in the regulation of mitochondrial lipids, leading to increase of mitochondrial mass. Potential oncogene.

Molecular Weight: 33811

NCBI Accession: NP_071413

UniProt: Q9H4A6