MIA3 antibody (AA 1-120)

Catalog No. ABIN1885584

The Rabbit Polyclonal anti-MIA3 antibody (ABIN1885584) specifically detects MIA3 in WB, IF and IHC. The antibody is reactive with Human samples.

Quick Overview for MIA3 antibody (AA 1-120) (ABIN1885584)

Target: MIA3 (Melanoma Inhibitory Activity Family, Member 3 (MIA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MIA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-MIA3 Antibody

Binding Specificity: AA 1-120

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 120 of Human MIA3

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for MIA3

Target: MIA3 (Melanoma Inhibitory Activity Family, Member 3 (MIA3))

Alternative Name: MIA3

Background: Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers.May participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier.Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading.However, it may participate in secretion of other proteins in cells that do not secrete COL7A1.

Molecular Weight: 214 kDa

Gene ID: 375056

NCBI Accession: XP_496436, XM_496436