TRIM23
Reactivity: Human
ELISA
Host: Mouse
Monoclonal
2G4
unconjugated
Application Notes
Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.100-1.250 Immunofluorescence: 1.100-1.200
Restrictions
For Research Use only
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
TRIM23
(Tripartite Motif Containing 23 (TRIM23))
Alternative Name
TRIM23
Background
The protein encoded by this gene is a member of the tripartite motif (TRIM) family.The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region.This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins.Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site.The protein localizes to lysosomes and the Golgi apparatus.It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation.Three alternatively spliced transcript variants for this gene have been described.[provided by RefSeq] Synonyms: ARD1, ARFD1, RNF46