Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.50-1.500 Immunofluorescence: 1.100-1.200
Restrictions
For Research Use only
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
TRIM63
(Tripartite Motif Containing 63 (TRIM63))
Alternative Name
MURF1
Background
This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris.The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere.In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity.Another member of this protein family binds to microtubules.Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle.[provided by RefSeq]