CRYbA4 antibody (AA 1-150)

Catalog No. ABIN1885644

This anti-CRYbA4 antibody is a Rabbit Polyclonal antibody detecting CRYbA4 in WB and IF. Suitable for Human.

Quick Overview for CRYbA4 antibody (AA 1-150) (ABIN1885644)

Target: CRYbA4 (Crystallin, beta A4 (CRYbA4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRYbA4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-CRYbA4 Antibody

Binding Specificity: AA 1-150

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 150 of Beta-crystallin A4

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for CRYbA4

Target: CRYbA4 (Crystallin, beta A4 (CRYbA4))

Alternative Name: Beta-crystallin A4

Background: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous.The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens.Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins.Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily.Alpha and beta families are further divided into acidic and basic groups.Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions.Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group).Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins.This gene, a beta acidic group member, is part of a gene cluster with beta-B1, beta-B2, and beta-B3.[provided by RefSeq]

Molecular Weight: 22 kDa

Gene ID: 1413

NCBI Accession: NM_001886, NP_001877