AP-2M1 (AA 1-160) antibody

Catalog No. ABIN1885659

The Rabbit Polyclonal anti-AP-2M1 antibody (ABIN1885659) specifically detects AP-2M1 in IHC and WB. The antibody is reactive with Human samples.

Quick Overview for AP-2M1 (AA 1-160) antibody (ABIN1885659)

Target: AP-2M1

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Product Details

Binding Specificity: AA 1-160

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 160 of Human AP2M1

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details

Target: AP-2M1

Background: This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family.The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes.The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein.Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]

Molecular Weight: 50 kDa

Gene ID: 1173

NCBI Accession: NM_004068, NP_004059