GSTa2 antibody (AA 1-166)

Catalog No. ABIN1885674

This anti-GSTa2 antibody is a Rabbit Polyclonal antibody detecting GSTa2 in WB, IHC and IF. Suitable for Human.

Quick Overview for GSTa2 antibody (AA 1-166) (ABIN1885674)

Target: GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSTa2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-GSTa2 Antibody

Binding Specificity: AA 1-166

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 166 of Human GSTA2

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for GSTa2

Target: GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))

Alternative Name: glutathione S-transferase alpha 2

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families.These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.The genes encoding these enzymes are known to be highly polymorphic.These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs.At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta.This gene encodes a glutathione S-tranferase belonging to the alpha class.The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver.In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.[provided by RefSeq]
Synonyms: GST2, GTA2, GTH2, GSTA2-2, MGC10525

Molecular Weight: 26 kDa

Gene ID: 2939

NCBI Accession: NP_000837, NM_000846