RGS10
Reactivity: Human
WB
Host: Mouse
Polyclonal
unconjugated
Application Notes
Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.100-1.250
Restrictions
For Research Use only
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
RGS10
(Regulator of G-Protein Signaling 10 (RGS10))
Alternative Name
RGS10
Background
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins.RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes.They drive G proteins into their inactive GDP-bound forms.Regulator of G protein signaling 10 belongs to this family.All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain.This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits.Regulator of G protein signaling 10 protein is localized in the nucleus.Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]