RGS4 antibody (AA 1-198)

Catalog No. ABIN1885758

This anti-RGS4 antibody is a Rabbit Polyclonal antibody detecting RGS4 in WB and IHC. Suitable for Human.

Quick Overview for RGS4 antibody (AA 1-198) (ABIN1885758)

Target: RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RGS4 Antibody

Binding Specificity: AA 1-198

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 198 of RGS4

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for RGS4

Target: RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Alternative Name: RGS4

Background: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins.RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes.They drive G proteins into their inactive GDP-bound forms.Regulator of G protein signaling 4 belongs to this family.All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain.Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4.This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq]

Molecular Weight: 23 kDa

Gene ID: 5999

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling