BIRC7 antibody (AA 1-211)
Quick Overview for BIRC7 antibody (AA 1-211) (ABIN1885779)
Target
See all BIRC7 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-211
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Purification
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 211 of ML-IAP
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Application Notes
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
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Alternative Name
- ML-IAP
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Background
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The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain.The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone.Two transcript variants encoding different isoforms have been found for this gene.The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.[provided by RefSeq]
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Molecular Weight
- 33 kDa
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Gene ID
- 79444
Target
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