Suggested dilutions: Western blotting: 1.500-1.3000 Immunofluorescence: 1.100-1.200
Restrictions
For Research Use only
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
AIMP1
(Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))
Alternative Name
EMAP II
Background
The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing.The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor.The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells.This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells.Multiple transcript variants encoding different isoforms have been found for this gene.A pseudogene has been identified on chromosome 20.[provided by RefSeq] Synonyms: p43, AIMP1, EMAP2, EMAPII