Factor XI antibody (AA 1-282)

Catalog No. ABIN1885884

This anti-Factor XI antibody is a Rabbit Polyclonal antibody detecting Factor XI in WB and IHC. Suitable for Human.

Quick Overview for Factor XI antibody (AA 1-282) (ABIN1885884)

Target: Factor XI (F11) (Coagulation Factor XI (F11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Factor XI antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Factor XI Antibody

Binding Specificity: AA 1-282

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 282 of Human F11

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for Factor XI

Target: Factor XI (F11) (Coagulation Factor XI (F11))

Alternative Name: Factor XI

Background: This gene encodes coagulation factor XI of the blood coagulation cascade.This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds.During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds.This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX.Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.[provided by RefSeq]

Molecular Weight: 70 kDa

Gene ID: 2160

NCBI Accession: NP_000119, NM_000128