LIG3 antibody (AA 116-403)

Catalog No. ABIN1885971

This anti-LIG3 antibody is a Rabbit Polyclonal antibody detecting LIG3 in WB and IHC. Suitable for Human.

Quick Overview for LIG3 antibody (AA 116-403) (ABIN1885971)

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIG3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-LIG3 Antibody

Binding Specificity: AA 116-403

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 116 and 403 of DNA ligase 3

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for LIG3

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Alternative Name: DNA ligase 3

Background: This gene is a member of the DNA ligase family.Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism.The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus.Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.[provided by RefSeq]

Molecular Weight: 113 kDa

Gene ID: 3980

NCBI Accession: NP_039269, NM_013975

Pathways: DNA Damage Repair