CASQ2 antibody (AA 124-398)

Catalog No. ABIN1885992

This anti-CASQ2 antibody is a Rabbit Polyclonal antibody detecting CASQ2 in WB and IHC. Suitable for Human.

Quick Overview for CASQ2 antibody (AA 124-398) (ABIN1885992)

Target: CASQ2 (Calsequestrin 2 (CASQ2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASQ2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CASQ2 Antibody

Binding Specificity: AA 124-398

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 124 and 398 of Human CASQ2

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for CASQ2

Target: CASQ2 (Calsequestrin 2 (CASQ2))

Alternative Name: Calsequestrin-2

Background: The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family.Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells.The protein is a calcium binding protein that stores calcium for muscle function.Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.[provided by RefSeq]

Molecular Weight: 46 kDa

Gene ID: 845

NCBI Accession: NP_001223, NM_001232

Pathways: Negative Regulation of Transporter Activity