CASQ2 antibody (AA 219-300)

Catalog No. ABIN7146585

Product Details anti-CASQ2 Antibody

Target: CASQ2 (Calsequestrin 2 (CASQ2))

Binding Specificity: AA 219-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASQ2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Calsequestrin-2 protein (219-300AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CASQ2

Target: CASQ2 (Calsequestrin 2 (CASQ2))

Alternative Name: CASQ2 (CASQ2 Products)

Synonyms: CASQ2 antibody, DKFZp468D075 antibody, AA033488 antibody, AW146219 antibody, ESTM52 antibody, cCSQ antibody, PDIB2 antibody, cardCSQ antibody, CASQ1 antibody, CAL antibody, calsequestrin 2 antibody, CASQ2 antibody, Casq2 antibody

Background:

Background: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits. Can bind around 60 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2, this plays an important role in triggering muscle contraction. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats.

Aliases: AA033488 antibody, AW146219 antibody, Calsequestrin 2 (cardiac muscle) antibody, Calsequestrin 2 fast twitch cardiac muscle antibody, Calsequestrin antibody, Calsequestrin cardiac muscle isoform antibody, Calsequestrin fast twitch cardiac muscle antibody, Calsequestrin-2 antibody, Calsequestrin2 antibody, cardCSQ antibody, Cardiac calsequestrin 2 antibody, cardiac muscle isoform antibody, CASQ 2 antibody, CASQ2 antibody, CASQ2_HUMAN antibody, cCSQ antibody, ESTM52 antibody, FLJ26321 antibody, FLJ93514 antibody, PDIB2 antibody

UniProt: O14958

Pathways: Negative Regulation of Transporter Activity