IL-24 antibody (AA 142-156)

Catalog No. ABIN1886040

This anti-IL-24 antibody is a Rabbit Polyclonal antibody detecting IL-24 in WB. Suitable for Human.

Quick Overview for IL-24 antibody (AA 142-156) (ABIN1886040)

Target: IL-24 (IL24) (Interleukin 24 (IL24))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-24 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IL-24 Antibody

Binding Specificity: AA 142-156

Purification: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 142 and 156 (Q13007) of IL24

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for IL-24

Target: IL-24 (IL24) (Interleukin 24 (IL24))

Alternative Name: Interleukin-24

Background: This gene encodes a member of the IL10 family of cytokines.It was identified as a gene induced during terminal differentiation in melanoma cells.The protein encoded by this gene can induce apoptosis selectively in various cancer cells.Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis.The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes.Alternatively spliced transcript variants encoding distinct isoforms have been reported.[provided by RefSeq]
Synonyms: C49A, FISP, IL-24, IL10B, MDA7, Mob-5, ST16, mda-7

Molecular Weight: 24 kDa

Gene ID: 11009

NCBI Accession: NP_006841, NM_006850

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy