FH antibody (AA 195-443)

Catalog No. ABIN1886155

This Rabbit Polyclonal antibody specifically detects FH in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for FH antibody (AA 195-443) (ABIN1886155)

Target: FH (Fumarate Hydratase (FH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FH antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-FH Antibody

Binding Specificity: AA 195-443

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 195 and 443 of fumarate hydratase

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for FH

Target: FH (Fumarate Hydratase (FH))

Alternative Name: fumarate hydratase

Background: The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate.It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used.The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm.It is similar to some thermostable class II fumarases and functions as a homotetramer.Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.[provided by RefSeq]

Molecular Weight: 55 kDa

Gene ID: 2271

NCBI Accession: NP_000134, NM_000143