GCM2
Reactivity: Human
WB, IF (cc), IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 750
Application Notes
Suggested dilutions: Western blotting: 1.500-1.3000
Restrictions
For Research Use only
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
GCM2
(Glial Cells Missing Homolog 2 (GCM2))
Alternative Name
glial cells missing homolog 2
Background
This gene is a homolog of the Drosophila glial cells missing gene, which is thought to act as a binary switch between neuronal and glial cell determination.The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity.The protein is a transcription factor that acts as a master regulator of parathyroid development.It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells.Mutations in this gene are associated with hypoparathyroidism.[provided by RefSeq]