ALDH1A2
Reactivity: Human, Mouse, Rat, Monkey
WB, IHC, IF, IC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Suggested dilutions: Western blotting: 1.500-1.3000
Restrictions
For Research Use only
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
ALDH1A2
(Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))
Alternative Name
ALDH1A2
Background
This protein belongs to the aldehyde dehydrogenase family of proteins.The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde.Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues.The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida.Three transcript variants encoding distinct isoforms have been identified for this gene.[provided by RefSeq]