ALDH1A2 antibody

Catalog No. ABIN7242827

The Rabbit Polyclonal anti-ALDH1A2 antibody is suitable to detect ALDH1A2 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for ALDH1A2 antibody (ABIN7242827)

Target: ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH1A2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ALDH1A2 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human ALDH1A2

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:25-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ALDH1A2

Target: ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))

Alternative Name: ALDH1A2

Background: This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.

Molecular Weight: 57 kDa

NCBI Accession: NP_001193826

UniProt: O94788

Pathways: Retinoic Acid Receptor Signaling Pathway