Lamin B1 antibody (AA 289-544)

Catalog No. ABIN1886320

This Rabbit Polyclonal antibody specifically detects Lamin B1 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Lamin B1 antibody (AA 289-544) (ABIN1886320)

Target: Lamin B1 (LMNB1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lamin B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Lamin B1 Antibody

Binding Specificity: AA 289-544

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 289 and 544 of Human LMNB1

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for Lamin B1

Target: Lamin B1 (LMNB1)

Alternative Name: Lamin B1

Background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane.The lamin family of proteins make up the matrix and are highly conserved in evolution.During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated.Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression.Vertebrate lamins consist of two types, A and B.This gene encodes one of the two B type proteins, B1.[provided by RefSeq]

Molecular Weight: 66 kDa

Gene ID: 4001

NCBI Accession: NP_005564, NM_005573

Pathways: Apoptosis, Caspase Cascade in Apoptosis